CME Group CEO Terry Duffy has voiced concern about the potential U.S. approval of crypto perpetual contracts, warning that the introduction of such products into regulated American markets could pose systemic risks to the broader financial system. Duffy made the remarks at the Piper Sandler Global Exchange and Fintech Conference on June 4, 2026, according to a transcript of the presentation. The comments come as U.S. regulators have begun opening the door to perpetual futures products that were previously confined to offshore venues.